Tom Six has directed exactly one kind of film: the kind most studios won't touch. Now, eleven years after The Human Centipede 3, the Dutch filmmaker is releasing his final project and revealing, for the first time, that he has been living with multiple sclerosis for 14 years.

Six disclosed the diagnosis in an exclusive with Variety alongside the announcement of The End of Tom Six. The film was shot over six years while he lived in isolation in his Amsterdam home, co-directed by Maartje Willems, and stars Edwin Alofs, Demian Kurosa, and Servaes Nelissen.

The catalyst for both the health crisis and this final project was The Onania Club, a 2019 satirical film that never received commercial distribution. According to Variety, the prolonged fight for a release "accelerated his disease and totally ravaged his body up to the point that he is now nearing the end of his life." Six himself pointed to a film industry "dominated by political correctness" as the reason the film was shut out.

Described in official materials as a "hilarious fever-dream-like documentary feature" about "the absurdity of existence, the film industry, his demise and the restrictions of artistic freedom," The End of Tom Six bypasses traditional distribution entirely. It arrives on YouTube on August 15 on a pay-what-you-want basis, with a DVD edition also available.

This is his first film in ten years. It will be his last.